Antipsychotic dosing: found in translation
نویسندگان
چکیده
منابع مشابه
Antipsychotic dosing: found in translation.
In the field of schizophrenia research, as in other areas of psychiatry, there is a sense of frustration that greater advances have not been made over the years, calling into question existing research strategies. Arguably, many purported gains claimed by research have been "lost in translation," resulting in limited impact on diagnosis and treatment in the clinical setting. There are exception...
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Conventional antipsychotics Dosing Optimal dosing with conventional antipsychotic agents involves the selection of a moderate initial dose (Table), followed by careful clinical titration to maximize antipsychotic efficacy while minimizing extrapyramidal symptoms (EPS). (If EPS develop on a typical drug, consider decreasing dose or adding an anticholinergic drug or switching to an atypical, if p...
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Since the identification of the hepatitis C virus (HCV) and subsequent cloning of its genome in 1989, only relatively modest progress had been made in the treatment of its chronic infection until recently. Interferon-alfa was approved in 1991 for the treatment of HCV infection, and provided a sustained virological response (SVR) of 9% for genotype 1, and 20–30% for genotypes 2 and 3. With the a...
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EVERY YEAR, THE 12 SCIENTIFIC SECTIONS of the American Physiological Society each select a physiologist prominent in its scientific domain to deliver a distinguished, named lecture at the Society’s annual meeting (Experimental Biology). In 2011, the Environmental and Exercise Physiology section chose Michael Joyner, MD, from the Mayo Clinic for this honor, named the Edward Adolph Lecture. Joyne...
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We highlight the value of carefully designed observational epidemiologic analyses in translating basic science discoveries to clinical application and in providing the impetus for exploring underlying mechanisms for observed associations. Coupling epidemiologic data with an in vitro screen of commonly used therapeutic agents may identify novel applications for further clinical testing.
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ژورنال
عنوان ژورنال: Journal of Psychiatry & Neuroscience
سال: 2014
ISSN: 1180-4882
DOI: 10.1503/jpn.130191